### Insert model parameters

Model structure

**Parameter**

**Value**

**Variance (ω**

^{2})Absorption rate constant (/time)

Bioavailability (fraction)

Central volume of distribution (Volume)

Periperhal volume of distribution (Volume)

Periperhal volume of distribution 2 (Volume)

Q - central-peripheral (Volume/time)

Q - central-peripheral 2 (Volume/time)

Clearance (Volume/time)

**Residual error**

σ

^{2}proportionalσ

^{2}additive### Dosing and simulation information

**Route of administration**

**Dose (units)**

*(Add multiple cohorts: 100, 200, 300)*

**Infusion time (h)**

**Repeat dose every x hours**

#### Additonal simulation information

**Simulate for x hours**

**Start simulation at x hours**

**Simulated number of individuals per dosing level**

### Pharmacokinetic profiles

### Summary statistics

### Add user data

**Include user data**

Column headers should minimally include the following columns:

*ID,CONCENTRATION,TIME*

A

*DOSE*column can be added to stratify the data.